A Secret Weapon For https://www.ceesdekker.net
A Secret Weapon For https://www.ceesdekker.net
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Making use of single-molecule optical and AFM imaging and drive-spectroscopy procedures, we search for to unravel the mechanistic facets of the structure and dynamics of chromosomes. Our research passions include things like:
You regularly get involved in conversations about science and religion. You've got also written many publications on the subject. Don’t you believe that at some point We are going to know every little thing Which God’s role might be in excess of?
Multicolor imaging of the bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins
Considering that 2000, Dekker has shifted the most crucial target of his get the job done towards biophysics in which he research the Qualities of single biomolecules and cells using the equipment of nanotechnology. This alteration of area was driven by his fascination for that extraordinary functioning of biological molecular buildings, along with with the extensive-time period perspective that a lot of exciting discoveries is often envisioned in this field.[5] Existing traces of investigation in his biophysics team are from the parts of:[six]
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The coiled-coil in the human Rad50 DNA repair protein consists of unique segments of enhanced flexibility
MATLAB codes for data processing are offered at . Julia codes employed for numerical simulation can be found at .
Atomic force microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative vogue
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Resolving the action dimensions in condensin-pushed DNA loop extrusion identifies ATP binding since the phase-creating approach
In 1993 he was appointed as Associate Professor at Delft University of Know-how. Within the mid-nineties Dekker and his staff attained results with the invention from the electronic Houses of carbon nanotubes, the first single-molecule transistor and also other nanoscience.
Many new https://www.ceesdekker.net phenomena ended up identified, and he and his study team set up a number one place During this discipline of study. Dekker and his investigate group found out new physics of nanotubes and also explored the feasibility of molecular electronics. In 1998, they were the primary to build a transistor based on an individual nanotube molecule.
One example is, we consider the nucleopore complicated, a gateway between the mobile nucleus along with the cytoplasm. This is a very sophisticated process and so difficult to analyze in the cell, so we use biomimetics. We reconstruct holes after which you can insert specific components of the nucleopore advanced to study transportation by means of it at The one-molecule stage.’
It had been an exceptionally fascinating time, for the duration of which I been given lots of assist from Delft College of Technologies, the place I used to be a professor at some time, and I began many collaborations with molecular biologists. That aided me discover a whole lot.’